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Chunkang Xuezhi Capsule

Development stage: Unknown
Lead developer: Aoteqi Mongolian Medicine
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Chunkang Xuezhi Capsule is a Mongolian medicine developed by Inner Mongolia Aoteqi Mongolian Medicine Co., Ltd. for the treatment of primary hyperlipidemia. It is specifically indicated for patients presenting with the traditional Chinese medicine (TCM) and Mongolian medicine pattern of 'liver-spleen-kidney deficiency with phlegm and blood stasis.' The formulation is designed to regulate lipid metabolism, resolve phlegm, and remove blood stasis. It has been evaluated in Phase II randomized, double-blind, placebo-controlled clinical trials in China to assess its efficacy and safety in adults with primary hyperlipidemia.

Brand names: Chunkang Xuezhi Capsule
Other names: 春康血脂胶囊Chun Kang Xue Zhi Jiao Nang

Targets

NTCP (Na+-taurocholate cotransporting polypeptide)NPC1L1 (Niemann-pick C1-Like 1 transporter)CYP7A1 (Cholesterol 7alpha-hydroxylase)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)ABCB11 (Bile salt export pump)

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