ciclesonide

Ciclesonide is a synthetic, nonhalogenated corticosteroid (glucocorticoid) used primarily as an inhaled or intranasal agent for the prevention and control of asthma and allergic rhinitis symptoms. It acts as a prodrug that is enzymatically converted in the body to its active metabolite, des-ciclesonide (RM1), which has high affinity for the glucocorticoid receptor. By binding to these receptors, ciclesonide exerts potent anti-inflammatory effects through inhibition of leukocyte infiltration, suppression of inflammatory mediators (such as prostaglandins and leukotrienes), and modulation of gene expression involved in immune responses. Ciclesonide is not effective for acute asthma attacks but reduces airway inflammation when used regularly[1][2][3][4][5][6].

Brand names

AlvescoOmnarisZetonnaAservo EquiHaler

Other names

Ciclesonidaciclesonidum