Drug intelligence / Profile preview

ciclesonide + fluticasone propionate + salmeterol

Development stage
Phase 3
Lead developer
AstraZeneca
Modality
Small Molecules
Administration
Inhalation, Intranasal
01

Overview

This is a combination therapy consisting of ciclesonide (an inhaled corticosteroid), fluticasone propionate (an inhaled corticosteroid), and salmeterol (a long-acting beta2-adrenergic agonist). Clinical studies have investigated the administration of ciclesonide alongside the fixed combination of fluticasone propionate/salmeterol, particularly examining their effects on cortisol suppression in patients with allergic rhinitis and asthma. The combination has been studied for its efficacy in managing asthma and allergic rhinitis.

02

Targets

ADRB2 (β2)GR (Glucocorticoid receptor)

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