ciclonicate

Ciclonicate is a small molecule vasodilator and a nicotinic acid derivative, specifically the trans-3,3,5-trimethylcyclohexyl ester of nicotinic acid. Developed primarily for the treatment of peripheral vascular diseases, it was historically utilized to manage obliterative arteriopathy of the lower limbs and arteriosclerotic peripheral vascular disorders. The drug functions by promoting vasodilation, thereby improving blood flow in patients suffering from atherosclerotic conditions, particularly those classified under Fontaine's stage II. Clinical evaluation of the compound was most active during the early 1980s, particularly in Italy, though it is no longer a mainstay in modern vascular therapy.

Brand names

Cicloergina

Other names

trans-3,3,5-trimethylcyclohexyl nicotinateciclonicato