Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ciclopirox (Polichem)
- Development stage
- Unknown
- Lead developer
- Polichem
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Ciclopoli Nail Lacquer is an approved, water-soluble topical antifungal treatment developed by Polichem SA (a subsidiary of Almirall) for the treatment of mild to moderate onychomycosis. The formulation contains 8% ciclopirox, a broad-spectrum antifungal agent, integrated into a proprietary transungual delivery system using hydroxypropyl-chitosan (HPCH). Unlike traditional nail lacquers that require organic solvents for removal, this hydro-alcoholic solution is water-soluble and enhances the penetration of ciclopirox deep into the nail plate. Ciclopirox exerts its antifungal effect by chelating polyvalent cations (such as Fe3+ and Al3+), which inhibits metal-dependent enzymes like cytochromes, catalase, and peroxidase, leading to the disruption of fungal cellular metabolism and cell wall integrity.
- Brand names
- CiclopoliPolinailNiogermoxNiogermosKitonailFulcareRejuvenailMyconailPrivex
- Other names
- ciclopirox 8% HPCH nail lacquerciclopirox hydroxypropyl-chitosan nail lacquer
02
Targets
NeuraminidaseCyp (Cyclophilin family)DOHH (Deoxyhypusine hydroxylase)Fe2+ (Ferrous iron)Fe3+ (Ferric iron)LPO (Lactoperoxidase)RRM2
Beyond the preview
Go deeper on ciclopirox (Polichem).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ciclopirox (Polichem).