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CICRVax6 is an investigational immunotherapy developed by the Centre for Immunology and Cancer Research (CICR) at the University of Queensland for the treatment of recurrent respiratory papillomatosis (RRP). It is a monovalent vaccine consisting of Human Papillomavirus (HPV) type 6 L1 virus-like particles (VLPs), which are non-infectious, self-assembling protein structures derived from the major capsid protein of HPV-6. The drug is designed to elicit a type-specific humoral and cellular immune response against HPV-6 to prevent or delay the recurrence of benign papilloma growths in the respiratory tract following conventional surgical treatment.
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