Drug intelligence / Profile preview

cidan capsule

Development stage
Phase 4
Lead developer
Weida Pharmaceutical
Administration
Oral
01

Overview

Cidan capsule is an orally administered, China-marketed traditional Chinese medicine formula used as an adjunctive antineoplastic treatment for primary liver cancer, including hepatocellular carcinoma. It is a heterogeneous medicinal mixture containing artificial bezoar, strychnos powder, borneol, and botanical or natural-material preparations including zedoary rhizome, Cremastra appendiculata pseudobulb, Brucea javanica seed, beehive, Bombyx batryticatus, Salvia miltiorrhiza root, Astragalus root, and Angelica. Its proposed anticancer activity is multi-component and multi-target rather than attributable to a single defined active pharmaceutical ingredient; preclinical studies report reduced tumor-cell proliferation, apoptosis induction, cell-cycle arrest, and reduced COX-2 and VEGF expression. ([cancer.gov](https://www.cancer.gov/publications/dictionaries/cancer-drug/def/cidan-herbal-capsule))

Other names
Ci Dan CapsuleCi Dan JiaonangCidanCidan herbal capsuleCidan JiaonangZedoary rhizome/Pseudobulbus cremastrae seu pleiones/Yatantzu/Strychni pulveratum/beehive/artificial bezoar/Bombyx mori/Danshen root/Radix astragali/Angelica/camphol alcohol capsule慈丹胶囊
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)VEGFA (Vascular endothelial growth factor A)

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