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Cigarette 2
- Development stage
- Unknown
- Lead developer
- University of Southern California
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
Cigarette 2 is an experimental nicotine-delivery intervention used in clinical research conducted by the University of Southern California. Specifically utilized in studies exploring the intersection of obsessive-compulsive disorder (OCD) symptoms and tobacco dependence, this intervention involves cigarettes with controlled nicotine content, ranging from 0 mg to a standard level of 0.8 mg. The primary objective of using these cigarettes in a research setting is to evaluate the behavioral and physiological mechanisms of nicotine addiction and withdrawal under varying levels of exposure. By manipulating nicotine dosage, researchers can observe how different levels of the drug interact with psychiatric symptoms to influence smoking behavior.
- Brand names
- Cigarette 2Cigarette2Cigarette-2
- Other names
- Nicotine cigarette
02
Targets
α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)
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