Cilidin

Cilidin is a cardiovascular medication containing the active ingredient cilnidipine, a fourth-generation calcium channel blocker. Marketed by Lloyd Healthcare as a small molecule generic formulation, it is primarily indicated for the treatment of hypertension and related cardiovascular conditions. Cilidin is distinguished by its dual mechanism of action, inhibiting both L-type and N-type voltage-gated calcium channels. While L-type channel blockade in vascular smooth muscle leads to vasodilation and reduced blood pressure, the inhibition of N-type channels in sympathetic nerve endings suppresses the release of norepinephrine. This dual action helps prevent reflex tachycardia and is particularly beneficial for patients with stress-induced hypertension. Additionally, Cilidin is noted for its renoprotective properties, making it an effective option for managing hypertension in patients with diabetes by helping to preserve kidney health and reduce proteinuria.

Brand names

Cilidin

Other names

cilnidipine