Drug intelligence / Profile preview

Cillbact

Development stage
Unknown
Lead developer
Rantomo Lifesciences
Modality
Small Molecules
Administration
Intravenous
01

Overview

Cillbact is an injectable combination antibiotic developed and marketed by Rantomo Lifesciences. It consists of piperacillin, a broad-spectrum ureidopenicillin, and tazobactam, a beta-lactamase inhibitor, typically formulated in a 4:0.5 ratio (totaling 4.5 grams). Piperacillin exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Tazobactam serves to protect piperacillin from hydrolysis by various beta-lactamase enzymes, thereby extending its activity against beta-lactamase-producing bacteria. Cillbact is indicated for the treatment of moderate to severe infections, including nosocomial pneumonia, complicated intra-abdominal infections, and skin and skin structure infections.

Brand names
Cillbact
Other names
Cillbact 4.5 INJCillbact4.5 INJCillbact-4.5 INJCillbact 4.5 InjectionCillbact4.5 InjectionCillbact-4.5 Injection
02

Targets

PBP (Penicillin-binding protein family)Neuraminidase

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