cinnamomum cassia extract

*Cinnamomum cassia extract* is a botanical extract derived from the bark of the Cinnamomum cassia tree, commonly called Chinese cinnamon. It consists primarily of phenylpropanoids, with **cinnamaldehyde** as the major bioactive compound, often representing 60–80% of the volatile content depending on the extraction method. Other key constituents include coumarin, cinnamic acid, cinnamyl acetate, 2-methoxycinnamaldehyde, and eugenol. **Mechanism of action:** - Exhibits **antimicrobial effects**: C. cassia extract shows in vitro activity against multiple bacteria and fungi, attributed mainly to cinnamaldehyde, which disrupts microbial cell structure or metabolism[4][5]. - Demonstrates **anti-inflammatory activity**: The extract, particularly 2'-hydroxycinnamaldehyde, inhibits nitric oxide production and nuclear factor kappa-B (NF-κB) activation in inflammatory pathways[1][4]. - Shows **antioxidant effects**: The moderate content of phenolic compounds contributes to scavenging of free radicals and reduction of oxidative stress[1][5]. - **Other pharmacological actions**: Animal and in vitro studies suggest possible anti-diabetic, hypotensive, vasodilatory, and neuroprotective properties, largely via effects on enzymes like cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and modulation of calcium signaling in vascular smooth muscle[1][5]. Cinnamomum cassia extract is primarily marketed as a **dietary supplement** for general health, blood sugar control, antioxidant support, and food preservation, not as a pharmaceutical drug[6].

Other names

cassia extractchinese cinnamon extractcassia bark extractCinnamomum aromaticum extract