Drug intelligence / Profile preview

cinnovex

Development stage
Unknown
Lead developer
Cinnagen
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Intramuscular
01

Overview

Cinnovex is a biosimilar of interferon beta-1a, a recombinant protein produced in Chinese hamster ovary cells. It consists of 166 amino acids with a molecular weight of approximately 22.5 kDa and is glycosylated to match the natural human form. Cinnovex acts as an immunomodulator and is primarily used for the treatment of relapsing forms of multiple sclerosis (MS), where it reduces the frequency and severity of disease relapses and helps slow progression. The drug was developed by CinnaGen in collaboration with Fraunhofer Institute, making it one of the first biogeneric therapeutic proteins approved from a Fraunhofer laboratory[7][8]. Clinical studies have demonstrated its efficacy and safety profile comparable to that of Avonex (the reference product)[3][9]. It is administered as an intramuscular injection once weekly[4][6].

Brand names
Cinnovex
Other names
interferon beta-1a biosimilarrecombinant human interferon beta-1a
02

Targets

IFNAR (Immune system modulation via type I interferon receptor)

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