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cisplatin polymeric micelles

Development stage: Preclinical
Lead developer: NanoCarrier
Modality: Nanoparticles → Drug Delivery Systems, Small Molecules
Administration: Intravenous

Overview

Cisplatin polymeric micelles is a nanoparticle-based formulation of the platinum-containing chemotherapeutic agent cisplatin, currently under preclinical development by Anhui Taienkang Pharmaceutical. By encapsulating cisplatin within polymeric micelles, the formulation is designed to enhance the solubility and stability of the drug while facilitating targeted delivery to tumor tissues through the enhanced permeability and retention (EPR) effect. This approach aims to mitigate the severe side effects associated with conventional cisplatin therapy, such as nephrotoxicity, ototoxicity, and peripheral neuropathy, by maintaining lower systemic concentrations of free drug and improving the therapeutic index for various oncological indications.

Other names: 注射用顺铂聚合物胶束及辅料Cisplatin Polymeric Micelles for Injection

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