Cissus Plus

Cissus Plus is a dietary supplement and nutraceutical primarily composed of *Cissus quadrangularis* extract, a perennial plant of the grape family traditionally used in Ayurvedic medicine. It is widely utilized in the sports nutrition industry for its purported benefits in promoting bone health, accelerating fracture healing, and supporting joint integrity. The primary active constituents are believed to be ketosteroids, which may exhibit glucocorticoid antagonistic properties, thereby potentially reducing the catabolic effects of cortisol on bone and muscle tissue. Additionally, it is thought to stimulate signaling pathways involved in osteoblast differentiation and collagen synthesis. While often marketed for weight loss and metabolic support, its most recognized application is in the management of joint pain and connective tissue recovery. Some formulations under this name may also include synergistic ingredients such as Vitamin C, calcium, or green tea extract.

Brand names

Cissus Plus

Other names

Cissus quadrangularis extractHadjod extract