citalopram + zinc sulfate

Citalopram + zinc sulfate is a non-standardized combination of two agents: citalopram, a selective serotonin reuptake inhibitor (SSRI) antidepressant, and zinc sulfate, an inorganic salt used as a dietary supplement to provide elemental zinc. Citalopram acts by inhibiting the reuptake of serotonin in the central nervous system, thereby increasing serotonergic activity and improving symptoms of depression[5][6]. Zinc is an essential trace element involved in numerous enzymatic processes and has been studied for its potential role in modulating mood and supporting antidepressant efficacy. Clinical studies suggest that adjunctive zinc supplementation with SSRIs like citalopram may enhance reduction of depressive symptoms compared to SSRI therapy alone[3]. This combination does not represent a commercially available fixed-dose product but may be used off-label or as part of clinical research.