citiolone

Citiolone is a small molecule drug used primarily in liver therapy as a hepatoprotectant and antioxidant. It is a derivative of the amino acid cysteine and acts as a hydroxyl free radical scavenger, providing protection against oxidative stress. Its mechanism involves increasing glutathione levels and accelerating superoxide dismutase (SOD), thereby reducing cellular damage from reactive oxygen species. Citiolone has also been studied for its neuroprotective effects in models of neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease, where it inhibits oxidative stress-induced cytotoxicity. Additionally, it has been used as a mucolytic agent and for the treatment of chronic hepatitis[1][5][7][8].

Brand names

CitiolaseMucorexSitilon

Other names

citioloneCitiolonaCitiolonumDL-N-Acetylhomocysteine thiolactoneThioxidreneAcetamide, N-(tetrahydro-2-oxo-3-thienyl)-3-Acetamidotetrahydro-2-thiophenoneN-(2-Oxotetrahydrothiophenyl)acetamideN-Acetylhomocysteine thiolactoneN-Acetyl-dl-homocysteine thiolactone2-Acetamido–4–mercaptobutyric acid gamma-thiolactoneN-(2-Oxothiolan–3–yl)acetamideN-Acetylhmocysteinethiolactone