Drug intelligence / Profile preview

citric acid + magnesium oxide + sodium picosulfate

Development stage
Unknown
Lead developer
Faromed
Modality
Small Molecules
Administration
Oral
01

Overview

Faro-Lax is a fixed-dose combination bowel preparation medication containing sodium picosulfate, magnesium oxide, and anhydrous citric acid. Developed by Faromed, it is indicated for cleansing of the colon in preparation for colonoscopy, radiography, endoscopy, or surgery in adults. Sodium picosulfate is a stimulant laxative prodrug that is hydrolyzed by colonic bacteria to its active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), which directly stimulates colonic peristalsis. Magnesium oxide and citric acid react in water to form magnesium citrate, an osmotic laxative that draws water into the intestinal lumen, increasing stool volume and promoting evacuation. Together, these components provide a highly effective purgative effect to clear the bowel.

Brand names
CitrafleetClenpiqEzycolonFaro-LaxFarolaxPico-SalaxPicolightPicoprepPicosolutionPrepopik
Other names
citric acid, magnesium oxide, and sodium picosulfatesodium picosulfate, magnesium oxide, and anhydrous citric acidsodium picosulfate, magnesium oxide, and citric acidsodium picosulfate/magnesium oxide/citric acid

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