Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
citrus sinensis peel extract
- Development stage
- Unknown
- Lead developer
- Multan Medical and Dental College
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Citrus sinensis peel extract is a botanical product derived from the peel of the sweet orange. It is currently being investigated as an adjunctive therapy for type 2 diabetes mellitus and dyslipidemia. The extract is rich in bioactive polyphenols and flavonoids, such as hesperidin and polymethoxylated flavones, which are thought to exert antidiabetic and lipid-lowering effects. Its mechanism of action involves the inhibition of carbohydrate-hydrolyzing enzymes like alpha-amylase and alpha-glucosidase, as well as the modulation of lipid metabolism through pathways such as PPAR signaling. Clinical research led by Dr. Zeemal Iqbal at Multan Medical & Dental College evaluates its efficacy when added to standard treatments like metformin and statins.
- Other names
- sweet orange peel extractCitrus sinensis extract
02
Targets
PPARA (Peroxisome proliferator-activated receptor alpha)PPARG (Peroxisome proliferator-activated receptor gamma)AMY (Pancreatic alpha-amylase)Sucrase-IsomaltasePPAR (PPAR family)
Beyond the preview
Go deeper on citrus sinensis peel extract.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on citrus sinensis peel extract.