Drug intelligence / Profile preview

citrus unshiu peel extract

Development stage
Unknown
Lead developer
Oryza Oil & Fat Chemical
Administration
Oral, Topical
01

Overview

Citrus unshiu peel extract is a bioactive complex derived from the peel of the Satsuma mandarin (Citrus unshiu), primarily cultivated in East Asia. It is rich in flavonoids (notably naringin, hesperidin, rutin, poncirin), phenolic acids, vitamin C, carotenoids, coumarins, and fiber. In vitro and in vivo research supports activity as a skin-brightening agent through inhibition of tyrosinase (reducing melanin synthesis). Its antioxidant and anti-inflammatory properties have been linked to reduction in pro-inflammatory cytokines such as TNF-α, IL-1β, inhibition of COX-2 and iNOS, and downregulation of NF-κB signaling. Traditionally, it has been used in various Asian countries to treat digestive discomfort, common cold, bronchitis, and minor inflammatory conditions. Main uses include functional food, cosmetics (primarily as a whitening and anti-aging ingredient), and as a dietary supplement with potential health and wellness benefits[1][2][3][5].

Brand names
EosidinHesperutin vita PCitrus EX_Narirutin
Other names
CUPCitrus unshiu peelSatsuma mandarin peel extractSatsuma orange peel extract
02

Targets

NF-κBNOS2 (Nitric Oxide Synthase 2)TYR (Tyrosinase)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

Beyond the preview

Go deeper on citrus unshiu peel extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on citrus unshiu peel extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call