Drug intelligence / Profile preview

CitruSlim

Development stage
Unknown
Lead developer
HP Ingredients
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

CitruSlim is a proprietary dietary supplement formulated for weight management and metabolic health. It is a standardized blend of Citrus bergamia (bergamot) extract and Eurycoma longifolia (commonly known as tongkat ali), marketed as containing citrus flavanone-O-glycosides and other bioactive plant compounds. The supplement’s mechanism of action involves several pathways: - Activation of AMP-activated protein kinase (AMPK), the body’s master regulator of energy metabolism, which encourages fat burning over storage. - Modulation of hunger hormones, specifically reducing ghrelin (“hunger hormone”) and leptin (“satiety hormone”), to help control appetite. - Reduction in cortisol levels, thereby supporting stress management and potentially breaking the cycle of stress-induced eating. Clinical studies have shown that CitruSlim can significantly reduce body mass index (BMI) in overweight or obese individuals compared to placebo, with additional effects on lowering cortisol, cholesterol, triglycerides, and blood glucose[2][5][7]. The product is caffeine-free and 100% plant-based.

Brand names
CitruSlim
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)GHSR (Growth hormone secretagogue receptor)

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