Drug intelligence / Profile preview

CivaDerm

Development stage
Unknown
Lead developer
CivaTech Oncology
Modality
Small Molecules, Device-based Delivery → Drug Delivery Systems
Administration
Implant, Topical
01

Overview

CivaDerm refers to two distinct products marketed under the same name. 1. In the United States, **CivaDerm** is an FDA-approved, polymer-encapsulated, low dose rate (LDR) brachytherapy device designed for intra-operative or surface radiation treatment of skin cancer and other superficial lesions. It incorporates radioactive palladium (same as CivaSheet), features gold shielding for one-sided application, and is worn as a bandage for approximately five days to fully deliver the prescribed radiation dose. 2. In India and other markets, **CivaDerm** is a topical pharmaceutical (cream or shampoo) containing ciclopirox or a ciclopirox plus zinc pyrithione combination. It is used as an antifungal agent for external use in the treatment of dandruff, seborrheic dermatitis, fungal skin infections, and fungal nail infections. Its primary mechanism is the inhibition of fungal cell growth by interfering with cell membrane function[1][2][5][7][3].

Brand names
CivaDerm
02

Targets

CYP (Cytochrome P450 family)

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