Drug intelligence / Profile preview

CJ-30060

Development stage
Phase 1
Modality
Small Molecules
Administration
Oral
01

Overview

CJ-30060 is an investigational small molecule drug being evaluated primarily for the treatment of solid tumors, with a focus on aggressive cancers that have limited therapeutic options. It acts as a multi-targeted agent, functioning as a calcium channel blocker, angiotensin II receptor blocker (ARB), and HMG-CoA reductase inhibitor. The drug has been studied in clinical trials to assess its pharmacokinetics and safety compared to established therapies such as Exforge (amlodipine/valsartan) and Crestor (rosuvastatin). Its development suggests potential utility in oncology due to its combined mechanisms of action targeting multiple pathways relevant to tumor growth and survival[1][2][3][4].

02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)LTCC (Voltage-gated calcium channel (L-type))AGTR1 (Angiotensin II Type-1 receptor)

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