Drug intelligence / Profile preview

CKD-381

Development stage
Phase 1
Lead developer
Chong Kun Dang Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

CKD-381 is an investigational small molecule drug developed by Chong Kun Dang Pharmaceutical for the treatment of gastroesophageal reflux disease (GERD). It is classified as a new molecular entity and has undergone several phase 1 clinical trials in healthy volunteers to assess its pharmacokinetics, pharmacodynamics, and safety. The precise mechanism of action for CKD-381 has not been disclosed or defined in public sources. The drug is administered orally in tablet form[1][2].

Brand names
EsoDuo
Other names
CKD-381CKD381CKD 381
02

Targets

ATP4A (Potassium–transporting ATPase alpha chain 1)CYP3A4 (Cytochrome P450 3A4)CYP2C9 (Cytochrome P450 family 2 subfamily C member 9)CYP2C19 (Cytochrome P450 2C19)

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