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CKDB-308-2
- Development stage
- Preclinical
- Lead developer
- CKD Bio
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
CKDB-308-2 is a probiotic-based live biotherapeutic product (LBP) currently under development by CKDBiO for the treatment of metabolic dysfunction-associated steatohepatitis (MASH). As a microbial therapy, it is designed to modulate the gut microbiota and the gut-liver axis to address the underlying metabolic and inflammatory components of MASH, which was formerly known as non-alcoholic steatohepatitis (NASH). The drug candidate is currently in the preclinical stage of development.
- Other names
- CKDB-308-2-CKDBiO-probiotic-MASHCKDB308-2-CKDBiO-probiotic-MASHCKDB 308-2-CKDBiO-probiotic-MASH
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