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CKDB-326
- Development stage
- Preclinical
- Lead developer
- CKD Bio
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
CKDB-326 is a probiotic-based therapeutic candidate being developed by CKDBiO (Chong Kun Dang Bio) for the treatment of chronic cholestatic liver diseases, including Primary Sclerosing Cholangitis (PSC) and Primary Biliary Cholangitis (PBC). As a live biotherapeutic product, CKDB-326 is designed to modulate the gut-liver axis, potentially addressing the underlying inflammation and bile acid dysregulation characteristic of these autoimmune biliary diseases. The drug is currently in the preclinical/discovery stage of development.
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