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CKW22

Development stage: Preclinical
Lead developer: Prostemics
Modality: Recombinant Proteins and Enzymes, Stem Cell Therapies → Cell Therapies, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration: Topical

Overview

CKW22 is a preclinical-stage therapeutic consisting of stem cell-derived exosomes loaded with Transforming Growth Factor Beta 3 (TGF-β3) protein. Developed by Prostemics in partnership with CK-Exogene, it is designed for wound treatment. TGF-β3 is known for its role in scarless wound healing and regulating the inflammatory response. By using exosomes as a delivery vehicle, the therapy aims to enhance the regenerative potential of TGF-β3 while leveraging the innate bioactivity of stem cell-derived extracellular vesicles. The exosome platform provides a stable environment for the protein cargo and facilitates its delivery to target cells at the wound site, promoting tissue regeneration and minimizing fibrosis.

Other names: TGF-β3-loaded stem cell exosomeProstemics wound healing exosome

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