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CL22205
- Development stage
- Unknown
- Lead developer
- Eetho Brands
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
CL22205 is a standardized herbal extract derived from the roots of *Asparagus racemosus*, commonly known as Shatavari. It is developed as a natural therapeutic for female reproductive health, specifically targeting menstrual discomfort, perimenopausal symptoms, and hormonal imbalances. Clinical data suggests that CL22205 modulates the hypothalamic-pituitary-ovarian axis, leading to significant reductions in serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels, while increasing anti-Müllerian hormone (AMH) levels. These hormonal shifts help alleviate vasomotor symptoms (such as hot flashes), dysmenorrhea, and menstrual cramps. Furthermore, the extract is being investigated for its potential to improve bone mineral density and enhance skin and hair quality in menopausal and perimenopausal women.
- Other names
- Asparagus racemosus root extractShatavari root extractstandardized Asparagus racemosus root extract
02
Targets
LH (Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1)AMH (Anti-Müllerian hormone)
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