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A three-drug antibiotic regimen consisting of clarithromycin, rifampicin, and ethambutol, primarily used for the treatment of Mycobacterium avium complex (MAC) infections. This combination is recommended by the American Thoracic Society and the Infectious Diseases Society of America as a standard treatment approach for MAC pulmonary disease and other MAC infections. The regimen works through multiple mechanisms to combat mycobacterial infections and is typically administered for extended periods.
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