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Clarithromycin lactobionate is a semi-synthetic macrolide antibiotic and the lactobionate salt form of clarithromycin. It is primarily utilized for the treatment of various bacterial infections, particularly when parenteral administration is required. The lactobionate salt is specifically formulated to enhance the aqueous solubility of the drug, making it suitable for intravenous injection or infusion. Its mechanism of action involves binding to the 50S subunit of the bacterial ribosome, which inhibits protein synthesis by blocking the translocation of aminoacyl transfer-RNA and preventing the elongation of the peptide chain. Shandong Keyuan Pharmaceutical Co., Ltd. is a major manufacturer of this active pharmaceutical ingredient (API).
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