Drug intelligence / Profile preview

Clavicure

Development stage
Phase 4
Lead developer
Matins Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Clavicure is an oral fixed-dose combination antibiotic containing amoxicillin, a beta-lactam penicillin-class antibiotic, and clavulanic acid (as potassium clavulanate), a beta-lactamase inhibitor. Marketed by Matins Pharma, Clavicure is approved for the treatment of various bacterial infections, including respiratory tract infections (such as pneumonia, bronchitis, and sinusitis), otitis media, urinary tract infections, and skin and soft tissue infections. Amoxicillin works by binding to and inhibiting penicillin-binding proteins (PBPs), thereby disrupting bacterial cell wall synthesis and leading to cell lysis. Clavulanic acid acts as a suicide inhibitor of bacterial beta-lactamases, preventing the enzymatic degradation of amoxicillin and restoring its activity against beta-lactamase-producing resistant strains.

Brand names
ClavicureClavicure-625Clavicure625Clavicure 625Clavicure-625 LBClavicure625 LBClavicure 625 LBClavicure-Duo
Other names
amoxicillin + clavulanic acidamoxicillin-clavulanateamoxycillin + clavulanic acidco-amoxiclav
02

Targets

PBP (Penicillin-binding protein family)Neuraminidaseβ-lactamase

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