Drug intelligence / Profile preview

Clenil Compositum

Development stage
Unknown
Lead developer
Chiesi
Modality
Small Molecules
Administration
Inhalation, Nebulization
01

Overview

Clenil Compositum is a combination pharmaceutical product containing **beclomethasone dipropionate** (a synthetic corticosteroid with anti-inflammatory activity) and **salbutamol** (a selective beta2-adrenoceptor agonist used as a bronchodilator). It is primarily indicated for the management and prevention of symptoms in asthma, chronic obstructive pulmonary disease (COPD), and allergic respiratory conditions. Beclomethasone acts as a pro-drug, converted in the lungs to its active metabolite B-17-MP, exerting potent anti-inflammatory effects via glucocorticoid receptor agonism, which reduces airway swelling and irritation. Salbutamol rapidly relieves bronchospasm by stimulating beta2-adrenoceptors, leading to relaxation of airway smooth muscle and bronchodilation. The combination provides both quick relief of acute symptoms and long-term control of airway inflammation. The product is delivered by nebulization or aerosol. Developed and manufactured by Chiesi Pharmaceuticals[1][2][3][4][6][7][8].

Brand names
Clenil Compositum
Other names
Clenil Compositum NebClenil Compositum-A
02

Targets

ADRB1 (β1)ADRB2 (β2)GR (Glucocorticoid receptor)

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