Drug intelligence / Profile preview

clevudine + adefovir

Development stage
Unknown
Lead developer
Bukwang Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

A combination antiviral therapy consisting of clevudine and adefovir used for the treatment of hepatitis B virus (HBV) infection. The combination has demonstrated potent antiviral activity with a better resistance profile compared to clevudine monotherapy. Clevudine is a nucleoside analog already approved for HBV in South Korea and the Philippines, while adefovir is another established antiviral medication for HBV treatment.

Brand names
LevovirRevovirHepsera
Other names
clevudine and adefovir combinationclevudine plus adefovirclevudine and adefovir dipivoxil combination
02

Targets

HBV Pol (Hepatitis B virus polymerase)

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