CLIC1pep

**CLIC1pep** is a peptide targeting Chloride Intracellular Channel Protein 1 (**CLIC1**), a protein involved in ion channel function and implicated in cancer cell migration, invasion, and metastasis. CLIC1, typically cytoplasmic, translocates to the plasma membrane under oxidative stress to form chloride ion channels that regulate cell volume and motility in tumor microenvironments. CLIC1pep likely functions as a selective inhibitor peptide, designed to bind CLIC1 and block its channel activity or membrane insertion, thereby suppressing cancer progression. Developed as a research tool or potential therapeutic, it exemplifies peptide-based modulation of intracellular channels for oncology applications, leveraging high specificity and minimal off-target effects characteristic of targeted peptides.[1][2]