Climavita forte

Climavita forte is a Swissmedic-approved herbal medicinal product developed and marketed by Permamed for the relief of menopausal symptoms, including hot flashes, sweating, sleep disturbances, nervousness, and mood swings. The active ingredient is a dry extract of the Cimicifuga racemosa rhizome (black cohosh), with each film-coated tablet containing 13 mg of the extract. Climavita forte is characterized by its non-estrogenic, organ-selective mechanism of action, functioning as a selective estrogen receptor modulator (SERM) without exerting direct estrogenic effects on the uterus or breast tissue. Additionally, it modulates central nervous system pathways, acting as an agonist at the mu-opioid receptor, 5-HT7, 5-HT1A, and 5-HT1D serotonin receptors, and the dopamine D2 receptor, which collectively contribute to temperature regulation and emotional stability during menopause.

Brand names

ClimavitaClimavita forteClimavita neo

Other names

Cimicifuga racemosa rhizome dry extractblack cohosh extract