Drug intelligence / Profile preview

clindamycin + nicotinamide

Development stage
Unknown
Lead developer
Ardent Life Sciences
Modality
Small Molecules
Administration
Topical
01

Overview

Clinset-N is a topical combination therapy marketed by Ardent Life Sciences for the treatment of acne vulgaris. It contains clindamycin phosphate, a lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, and nicotinamide (niacinamide), a form of vitamin B3 with potent anti-inflammatory properties. Clindamycin targets *Cutibacterium acnes*, the primary bacterium associated with acne, while nicotinamide helps reduce redness, swelling, and sebum production. This combination is designed to address both the bacterial and inflammatory components of acne.

Brand names
Clinset-N
Other names
clindamycin phosphate + niacinamide
02

Targets

Bacterial 50S ribosomal subunit

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