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clindamycin phosphate + adapalene + benzoyl peroxide
- Development stage
- Approved
- Lead developer
- Valeant Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
**Clindamycin phosphate + adapalene + benzoyl peroxide** is a fixed-dose topical triple-combination acne treatment marketed as **Cabtreo**. It combines clindamycin phosphate, a lincosamide antibacterial that inhibits bacterial protein synthesis; adapalene, a retinoid that normalizes follicular keratinization and reduces inflammation; and benzoyl peroxide, an oxidizing antimicrobial with comedolytic activity. The gel is indicated for once-daily topical treatment of acne vulgaris in adults and pediatric patients aged 12 years and older.
- Brand names
- Cabtreo
- Other names
- clindamycin phosphate + adapalene + benzoyl peroxideclindamycin phosphate, adapalene, and benzoyl peroxide
02
Targets
Bacterial 50S ribosomal subunitRARG (Retinoic acid receptor gamma)RARB (Retinoic acid receptor beta)
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