Drug intelligence / Profile preview

clitoria ternatea extract

Development stage
Phase 1
Modality
Small Molecules
Administration
Oral
01

Overview

Clitoria ternatea extract, derived from the **Butterfly Pea** plant, is a bioactive botanical preparation rich in polyphenols, including anthocyanins (such as delphinidins), tannins, and clitorienolactones. The extract is widely investigated for its multi-target pharmacological properties, specifically its neuroprotective, antidiabetic, and antiobesity effects. In pre-clinical models, it has demonstrated the ability to mitigate hyperglycemia and weight loss, reduce oxidative stress, and inhibit the formation of **advanced glycation end products (AGEs)**, which are implicated in diabetic complications. Root-derived compounds like clitorienolactones A and B appear to modulate hippocampal neuroplasticity and improve cognitive function by sustaining intracellular calcium levels and interacting with **NMDA receptors**. Additionally, the extract's pH-sensitive anthocyanins make it a valuable natural colorant and an intelligent packaging indicator for monitoring food freshness in the food science industry.

Other names
butterfly pea extractclitoria ternatea petals aqueous extractclitoria ternatea root extractAsian pigeonwings extractblue pea extractbutterfly pea flower extract
02

Targets

AGEs (Advanced glycation end-products)

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