CLM-IN01

**CLM-IN01** is an investigational, single-prescription drug-device combination product from Closed Loop Medicine for chronic insomnia. It co-packages a novel 2 mg prolonged-release capsule formulation of an undisclosed known drug with Closed Loop Medicine's software as a medical device digital-therapeutic component, intended to integrate medication management and individualized digital care. The software component received UKCA marking and CE medical-device designation in 2021; the specific pharmacologic active ingredient and molecular target have not been publicly identified in the sources reviewed. ([closedloopmedicine.com](https://www.closedloopmedicine.com/closed-loop-medicine-secures-ukca-marking-and-receives-ce-designation-for-a-medical-device-that-will-form-part-of-its-insomnia-product-clm-in01/))