Drug intelligence / Profile preview

clobenzorex

Development stage
Unknown
Lead developer
Sanofi
Modality
Small Molecules
Administration
Oral
01

Overview

Clobenzorex is a central nervous system stimulant and anorectic drug, chemically classified as an N-substituted amphetamine and phenethylamine. It acts as a prodrug of amphetamine, being metabolized in the body to amphetamine and other metabolites such as 4-hydroxyclobenzorex. Its primary clinical use is as an appetite suppressant for the management of obesity. The drug exerts its effects by stimulating the release of norepinephrine and dopamine in the brain, leading to reduced appetite and increased satiety. Clobenzorex has been marketed under several brand names, including Asenlix, primarily in Mexico and parts of Latin America. It is supplied typically as hydrochloride salt in oral capsules[1][2][3][6][8].

Brand names
AsenlixDinintelFinedalRexigen
Other names
N-(2-chlorobenzyl)amphetamineClobenzorexum
02

Targets

DAT (Dopamine plasma membrane transport protein)NET (Norepinephrine Transporter)

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