Drug intelligence / Profile preview

clobetasone butyrate + hydrocortisone acetate

Development stage
Unknown
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Clobetasone butyrate + hydrocortisone acetate is a topical combination of two corticosteroids used to reduce inflammation, itching, and redness associated with various skin conditions such as eczema and dermatitis. Both components are synthetic glucocorticoid corticosteroids that act by suppressing the inflammatory response in the skin. Clobetasone butyrate is considered a moderately potent topical steroid, while hydrocortisone acetate is classified as mild to moderate in potency. The combination aims to provide enhanced anti-inflammatory effects for short-term management of steroid-responsive dermatoses.

02

Targets

GR (Glucocorticoid receptor)

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