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clomiphene citrate + ethinyl estradiol
- Development stage
- Preclinical
- Lead developer
- Procter & Gamble
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination therapy used in fertility treatment that pairs clomiphene citrate, a selective estrogen receptor modulator (SERM), with ethinyl estradiol, a synthetic estrogen. The addition of ethinyl estradiol helps reverse the negative effects of clomiphene citrate on endometrial thickness, potentially improving pregnancy rates in women undergoing ovulation induction and intrauterine insemination.
- Other names
- clomiphene + ethinyl estradiol
02
Targets
ESR2 (ERβ)ESR1 (ERα)
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