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ClorNovir
- Development stage
- Unknown
- Lead developer
- Dr. Ferrer Biopharma
- Modality
- Small Molecules
- Administration
- Intranasal
01
Overview
**ClorNovir** is an intranasal spray formulation of chlorpheniramine maleate (1%) developed by Dr. Ferrer BioPharma using advanced nanoparticle technology and GentleMist delivery for optimal nasal distribution. It functions as a **histamine H1 receptor antagonist** with broad-spectrum antiviral properties, targeting viral replication in the nasopharynx to provide rapid symptom relief in COVID-19 and influenza by blocking viral entry into cells, neutralizing virus at the nasal portal, and offering anti-inflammatory effects while bypassing hepatic metabolism for enhanced efficacy. Primarily indicated for early treatment of mild COVID-19 to accelerate clinical recovery and reduce hospitalizations, it was a CPhI awards finalist for COVID-19 innovation.[2][5][7]
- Brand names
- ClorNovir
- Other names
- Chlorpheniramine maleate 1% nasal spray
02
Targets
HRH1 (Histamine H1 Receptor)
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