Drug intelligence / Profile preview

ClorRelief

Development stage
Unknown
Lead developer
Dr. Ferrer Biopharma
Modality
Small Molecules
Administration
Intranasal
01

Overview

ClorRelief is an intranasal antihistamine spray developed by Dr. Ferrer BioPharma for the treatment of allergic rhinitis and nasal congestion. The product's active ingredient is chlorpheniramine maleate, a first-generation alkylamine antihistamine that functions as a potent antagonist of the histamine H1 receptor. By competitively inhibiting H1 receptors on effector cells, ClorRelief reduces the allergic inflammatory response, alleviating symptoms such as sneezing, rhinorrhea, and nasal pruritus. The formulation is part of Dr. Ferrer BioPharma's 'Clor' product line, which utilizes a proprietary intranasal delivery system intended to provide localized relief with potentially reduced systemic side effects compared to oral antihistamines. It is currently marketed as an approved over-the-counter (OTC) product for both adults and children.

Brand names
ClorReliefClorRelief Kids
02

Targets

mAChR (Muscarinic acetylcholine receptors)HRH1 (Histamine H1 Receptor)ADRA1A (α1A)TAS2R (Taste receptor type 2 family)5-HT (Serotonin receptors)

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