Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
closantel sodium
- Development stage
- Preclinical
- Lead developer
- Johnson & Johnson
- Modality
- Small Molecules
- Administration
- Oral, Subcutaneous, Intramuscular
01
Overview
Closantel sodium is a synthetic halogenated salicylanilide derivative used as a broad-spectrum anthelmintic in veterinary medicine. It is primarily indicated for the treatment and control of internal parasites in livestock, including the common liver fluke (*Fasciola hepatica*), blood-sucking gastrointestinal nematodes such as *Haemonchus contortus*, and larval stages of certain arthropods like the sheep nasal bot fly (*Oestrus ovis*). The drug's mechanism of action involves the uncoupling of mitochondrial oxidative phosphorylation in susceptible parasites, which disrupts ATP synthesis and leads to metabolic failure and death. Viyash Life Sciences is currently developing this small molecule in the preclinical stage for animal health applications.
- Brand names
- FlukiverSeponver
- Other names
- Sodium closantelClosantel sodium salt
02
Targets
CHIT1 (Chitotriosidase)SDH (Mitochondrial electron transport chain complex II)OXPHOS (Parasite mitochondrial oxidative phosphorylation system)Complex II (Succinate dehydrogenase)OXPHOS (Mitochondrial OXPHOS complexes)
Beyond the preview
Go deeper on closantel sodium.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on closantel sodium.