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Closone (HK inno.N Corporation)
- Development stage
- Phase 4
- Lead developer
- HK inno.N Corporation
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Closone** is a Korean fixed-dose oral dual-antiplatelet product developed and manufactured by **HK inno.N**. It contains **clopidogrel 75 mg** and **aspirin 100 mg** and is used for patients who require concomitant antiplatelet therapy, including patients with coronary artery disease, acute coronary syndrome, atherosclerotic disease, or thromboembolic risk. Clopidogrel irreversibly inhibits platelet P2Y12 ADP receptors after metabolic activation, while aspirin irreversibly inhibits platelet cyclooxygenase-1, suppressing thromboxane A2 formation. Together, these complementary mechanisms reduce platelet activation and aggregation.
- Brand names
- Closone
- Other names
- Closone Cap.클로스원캡슐
02
Targets
GR (Glucocorticoid receptor)PGHS-1 (Prostaglandin G/H Synthase 1)P2Y12 (Purinergic P2Y12 receptor)
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