Drug intelligence / Profile preview

ClotFoam

Development stage
Phase 1
Lead developer
Biomedica
Administration
Topical
01

Overview

ClotFoam is a novel hemostatic agent designed to control severe bleeding, particularly in intraoperative and trauma settings. Its mechanism of action is based on the rapid and powerful activity of fibrin monomer delivered via a foam with high affinity for endothelial tissue, enabling effective hemostasis without the need for compression. The product was developed to address unmet needs in gynecology (such as acute menstrual disorders and postpartum hemorrhage), combat trauma, emergency medicine, and solid organ surgery. ClotFoam has demonstrated promising results in animal models for large organ resection with minimally invasive application methods. Clinical trials are being conducted to establish its safety and efficacy as an adjunct in solid organ hemorrhage, with future plans for broader indications including primary treatment of trauma patients[1].

Brand names
ClotFoam
02

Targets

Fibrin knob-hole interface

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