Drug intelligence / Profile preview

CM-AT

Development stage
Phase 3
Lead developer
Curemark
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

CM-AT is a proprietary, high-potency oral enzyme replacement therapy developed by Curemark for the treatment of Autism Spectrum Disorder (ASD) in children. The therapy targets a specific physiological subset of the autism population characterized by a deficiency in fecal chymotrypsin, a biomarker identified by Curemark that indicates impaired protein digestion. By providing exogenous proteases, CM-AT aims to restore the availability of essential amino acids necessary for the synthesis of key neurotransmitters, thereby addressing the core behavioral and cognitive symptoms of ASD. The drug has completed Phase III clinical trials and received Fast Track designation from the FDA. Curemark has also explored the application of its enzyme platform for other neurological conditions, including schizophrenia, attention deficit hyperactivity disorder (ADHD), and Parkinson's disease.

Other names
Curemark Autism Therapy

Beyond the preview

Go deeper on CM-AT.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on CM-AT.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call