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CM500

Development stage
Phase 1
Lead developer
Lumina Pharmaceuticals
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration
Intravenous
01

Overview

CM500 is a peptide-based radiopharmaceutical developed by Lumina Pharmaceuticals for use as a diagnostic imaging agent in positron emission tomography (PET). It is being investigated in two radiolabeled forms: [64Cu]CM500 (copper-64) and [68Ga]CM500 (gallium-68). These tracers are designed to bind to specific targets on solid tumors, enabling high-resolution imaging via PET-MR or PET-CT. The primary objective of CM500 is to improve the detection of solid tumors throughout the body, potentially identifying smaller lesions than conventional imaging techniques. Early-phase clinical studies are focused on evaluating the safety, biodistribution, and pharmacokinetics of these tracers in both healthy volunteers and patients with cancer.

Other names
[64Cu]CM500[68Ga]CM500
02

Targets

Fibrin (Factor Ia)

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