Drug intelligence / Profile preview

CMAB806

Development stage
Unknown
Lead developer
China Antibody Pharmaceutical
Administration
Intravenous
01

Overview

CMAB806 is a recombinant humanized monoclonal antibody that targets interleukin-6 (IL-6). By binding directly to IL-6, it prevents the cytokine from interacting with its receptors (both soluble and membrane-bound), thereby inhibiting the downstream signaling pathways that lead to systemic inflammation. It was primarily developed to manage cytokine release syndrome (CRS), a severe immune overreaction often seen in patients with severe COVID-19 or following certain immunotherapies. The drug was investigated by researchers at Central South Hospital of Wuhan University during the COVID-1}

Other names
anti-IL-6 monoclonal antibodyanti-IL6 monoclonal antibodyanti-IL 6 monoclonal antibody
02

Targets

EGFR806 (Epidermal growth factor receptor (EGFR), 806 epitope)

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