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CMTS4520

Development stage: Phase 2
Lead developer: The Second Hospital of Nanjing Medical University
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral, Rectal

Overview

**CMTS4520** is an investigational, orally administered dietary-fiber and probiotic formulation described in registered clinical studies as a dietary fiber probiotic product. It is being evaluated by The Second Affiliated Hospital of Nanjing Medical University for chronic diarrhoea and chronic constipation, both as a standalone intervention and as an adjunct to washed microbiota transplantation. The individual probiotic strains, dietary-fiber components, dose, and molecular mechanism have not been publicly disclosed.

Other names: dietary fiber probiotics

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